Informatica does not allow to backup the repository and restore directly into a higher environment as the repository version changes across major versions. This video demonstrates the migration of Repository Service from a lower version to a higher version of PowerCenter.
How to automate the repository and domain back up process for disaster recovery in PowerCenter
Converting and adding of a self signed certificate to use a Webservice Consumer transformation
How to find in which host the Repository Integration service is running in a multi node domain